Deep Dives into Peptide Science
Research breakdowns, protocol design, and the latest findings from the world of peptide science. Written for researchers who care about the evidence.
Do GLP-1 Drugs Sabotage Fat Grafts? What the Latest Surgery Data Actually Shows
New studies show semaglutide users face a 45% complication rate in cosmetic surgery. Here's why GLP-1 drugs interfere with fat graft biology and what surgeons are doing about it.
Thymosin Alpha-1 in Cancer Immunotherapy: New Mechanism Restores Immunity After Chemo
Three 2026 studies reveal how thymosin alpha-1 restores antitumor immunity after chemotherapy, reverses T-cell exhaustion, and synergizes with checkpoint inhibitors.
Semaglutide Cuts Cardiovascular Events by 25% in Rheumatoid Arthritis Patients: New Study
A June 2026 study found semaglutide reduced major cardiovascular events by 25% and heart failure by 31% in obese adults with type 2 diabetes and rheumatoid arthritis, with a surprising bonus: fewer patients needed stronger RA medications.
GLP-1 Drugs and Your Lungs: What a New Systematic Review Actually Found
A new systematic review of 19 studies maps respiratory safety signals for GLP-1 receptor agonists. The findings are reassuring for most users, with one significant exception: aspiration risk during surgery.
Dulaglutide and Multiple Sclerosis: First GLP-1RA Trial Shows Walking Speed Improvements
A randomized trial found dulaglutide improved walking speed and manual dexterity in MS patients — the first human evidence that GLP-1 drugs may protect the brain beyond weight loss.
Tirzepatide vs Semaglutide: 2026 Real-World Data Crowns a Clear Winner
Two massive studies — 10,339 matched pairs in PNAS Nexus and 45,093 patients in The Lancet — deliver the clearest comparison yet of GLP-1 weight loss drugs. Tirzepatide wins on nearly every metric.
Amycretin Just Crushed Semaglutide in a Weight Loss Meta-Analysis. Here Is What the Data Actually Show.
A network meta-analysis of 6 RCTs found amycretin produced 24% weight loss versus semaglutide’s 11%. The amylin pathway is the next frontier in obesity treatment.
Semaglutide for Schizophrenia: GLP-1 Drugs May Save Lives in Psychiatry's Most Underserved Population
New clinical trials show semaglutide produces dramatic weight loss and metabolic improvements in people with schizophrenia on antipsychotics, without worsening psychiatric symptoms. A meta-analysis of 595 patients confirms the signal.
Retatrutide Cuts Blood Sugar and Weight in Landmark T2D Trial — Published in The Lancet
Eli Lilly’s triple-agonist peptide retatrutide reduced HbA1c by nearly 2% and body weight by 15.3% as monotherapy in a 537-person phase 3 trial published in The Lancet.
Ketone Esters Could Save Your Muscles on Semaglutide — New Study Shows
A new JCI Insight study finds that ketone ester supplementation preserves muscle mass during semaglutide-driven weight loss — without compromising fat loss.
GLP-1 Agonists Cut Atrial Fibrillation Risk Independent of Weight Loss
A 12,000-patient study presented at Heart Rhythm 2026 found GLP-1 receptor agonists reduce atrial fibrillation risk by 33%, even in patients who gained weight. Semaglutide showed the strongest effect.