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The Journal

Deep Dives into Peptide Science

Research breakdowns, protocol design, and the latest findings from the world of peptide science. Written for researchers who care about the evidence.

Survodutide Shrinks Liver Fat by 84% in Phase 3 Trial — A New Era for Fatty Liver Disease
Research

Survodutide Shrinks Liver Fat by 84% in Phase 3 Trial — A New Era for Fatty Liver Disease

A landmark Nature Medicine trial shows survodutide dramatically reduces liver fat and body weight in patients with fatty liver disease. Here's what the data actually says.

Jul 1, 2026Read more →
Why BPC-157 Still Hasn't Reached Clinical Trials After 30 Years of Research
Research

Why BPC-157 Still Hasn't Reached Clinical Trials After 30 Years of Research

BPC-157 has thousands of preclinical studies showing tissue-healing effects across nearly every organ system. So why does it still have zero completed clinical trials? A May 2026 review finally explains the gap.

Jun 30, 2026Read more →
Do GLP-1 Drugs Sabotage Fat Grafts? What the Latest Surgery Data Actually Shows
Research

Do GLP-1 Drugs Sabotage Fat Grafts? What the Latest Surgery Data Actually Shows

New studies show semaglutide users face a 45% complication rate in cosmetic surgery. Here's why GLP-1 drugs interfere with fat graft biology and what surgeons are doing about it.

Jun 28, 2026Read more →
Thymosin Alpha-1 in Cancer Immunotherapy: New Mechanism Restores Immunity After Chemo
Research

Thymosin Alpha-1 in Cancer Immunotherapy: New Mechanism Restores Immunity After Chemo

Three 2026 studies reveal how thymosin alpha-1 restores antitumor immunity after chemotherapy, reverses T-cell exhaustion, and synergizes with checkpoint inhibitors.

Jun 27, 2026Read more →
Semaglutide Cuts Cardiovascular Events by 25% in Rheumatoid Arthritis Patients: New Study
Research

Semaglutide Cuts Cardiovascular Events by 25% in Rheumatoid Arthritis Patients: New Study

A June 2026 study found semaglutide reduced major cardiovascular events by 25% and heart failure by 31% in obese adults with type 2 diabetes and rheumatoid arthritis, with a surprising bonus: fewer patients needed stronger RA medications.

Jun 25, 2026Read more →
GLP-1 Drugs and Your Lungs: What a New Systematic Review Actually Found
Research

GLP-1 Drugs and Your Lungs: What a New Systematic Review Actually Found

A new systematic review of 19 studies maps respiratory safety signals for GLP-1 receptor agonists. The findings are reassuring for most users, with one significant exception: aspiration risk during surgery.

Jun 23, 2026Read more →
Dulaglutide and Multiple Sclerosis: First GLP-1RA Trial Shows Walking Speed Improvements
Research

Dulaglutide and Multiple Sclerosis: First GLP-1RA Trial Shows Walking Speed Improvements

A randomized trial found dulaglutide improved walking speed and manual dexterity in MS patients — the first human evidence that GLP-1 drugs may protect the brain beyond weight loss.

Jun 22, 2026Read more →
Tirzepatide vs Semaglutide: 2026 Real-World Data Crowns a Clear Winner
Research

Tirzepatide vs Semaglutide: 2026 Real-World Data Crowns a Clear Winner

Two massive studies — 10,339 matched pairs in PNAS Nexus and 45,093 patients in The Lancet — deliver the clearest comparison yet of GLP-1 weight loss drugs. Tirzepatide wins on nearly every metric.

Jun 21, 2026Read more →
Amycretin Just Crushed Semaglutide in a Weight Loss Meta-Analysis. Here Is What the Data Actually Show.
Research

Amycretin Just Crushed Semaglutide in a Weight Loss Meta-Analysis. Here Is What the Data Actually Show.

A network meta-analysis of 6 RCTs found amycretin produced 24% weight loss versus semaglutide’s 11%. The amylin pathway is the next frontier in obesity treatment.

Jun 20, 2026Read more →
Semaglutide for Schizophrenia: GLP-1 Drugs May Save Lives in Psychiatry's Most Underserved Population
Research

Semaglutide for Schizophrenia: GLP-1 Drugs May Save Lives in Psychiatry's Most Underserved Population

New clinical trials show semaglutide produces dramatic weight loss and metabolic improvements in people with schizophrenia on antipsychotics, without worsening psychiatric symptoms. A meta-analysis of 595 patients confirms the signal.

Jun 19, 2026Read more →
Retatrutide Cuts Blood Sugar and Weight in Landmark T2D Trial — Published in The Lancet
Research

Retatrutide Cuts Blood Sugar and Weight in Landmark T2D Trial — Published in The Lancet

Eli Lilly’s triple-agonist peptide retatrutide reduced HbA1c by nearly 2% and body weight by 15.3% as monotherapy in a 537-person phase 3 trial published in The Lancet.

Jun 15, 2026Read more →