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Oria Health
The Journal

Deep Dives into Peptide Science

Research breakdowns, protocol design, and the latest findings from the world of peptide science. Written for researchers who care about the evidence.

GLP-1 Drugs, Anxiety, and Depression: What the New Data Actually Says
Research

GLP-1 Drugs, Anxiety, and Depression: What the New Data Actually Says

A large real-world study just compared semaglutide and tirzepatide to older weight-loss drugs on mental health outcomes. The results split in an unexpected direction.

Jul 12, 2026Read more →
Amylin Therapies: The Next Generation of Weight-Loss Drugs Beyond GLP-1s
Research

Amylin Therapies: The Next Generation of Weight-Loss Drugs Beyond GLP-1s

New clinical data from ADA 2026 and ECO 2026 shows amylin-based therapies delivering double-digit weight loss with better muscle preservation and fewer GI side effects than GLP-1s alone. Here's why every major pharma company is building an amylin program.

Jul 11, 2026Read more →
Survodutide Cuts Liver Fat by 63% and Visceral Fat by 34% — Why the Weight Loss Numbers Tell Only Half the Story
Research

Survodutide Cuts Liver Fat by 63% and Visceral Fat by 34% — Why the Weight Loss Numbers Tell Only Half the Story

The SYNCHRONIZE-1 trial showed survodutide delivers 16.6% weight loss, but the real story is what happens to the fat you can't see — deep visceral and liver fat that drives cardiometabolic disease.

Jul 8, 2026Read more →
FDA Scientists vs. RFK Jr.: The Evidence Battle That Could Decide Peptide Access
News

FDA Scientists vs. RFK Jr.: The Evidence Battle That Could Decide Peptide Access

FDA career scientists say there's insufficient evidence for all 7 peptides under review, directly contradicting RFK Jr.'s push to expand access. Here's what the briefing documents actually say.

Jul 6, 2026Read more →
The Hidden Impurity in Compounded Tirzepatide: What Lilly's Lab Found in Your B12 Combo
News

The Hidden Impurity in Compounded Tirzepatide: What Lilly's Lab Found in Your B12 Combo

Eli Lilly's analytical labs discovered a novel chemical impurity in compounded tirzepatide-B12 products—a compound formed by a reaction between the two ingredients that nobody has tested for safety.

Jul 4, 2026Read more →
VK2735: The Oral Weight Loss Pill That Lost 26 Pounds in 13 Weeks
Research

VK2735: The Oral Weight Loss Pill That Lost 26 Pounds in 13 Weeks

Viking Therapeutics just showed that their oral dual GLP-1/GIP agonist VK2735 produced 12.2% weight loss in 13 weeks — no injections required. Here's what the Phase 2 data means for the future of weight loss pills.

Jul 2, 2026Read more →
Survodutide Shrinks Liver Fat by 84% in Phase 3 Trial — A New Era for Fatty Liver Disease
Research

Survodutide Shrinks Liver Fat by 84% in Phase 3 Trial — A New Era for Fatty Liver Disease

A landmark Nature Medicine trial shows survodutide dramatically reduces liver fat and body weight in patients with fatty liver disease. Here's what the data actually says.

Jul 1, 2026Read more →
Why BPC-157 Still Hasn't Reached Clinical Trials After 30 Years of Research
Research

Why BPC-157 Still Hasn't Reached Clinical Trials After 30 Years of Research

BPC-157 has thousands of preclinical studies showing tissue-healing effects across nearly every organ system. So why does it still have zero completed clinical trials? A May 2026 review finally explains the gap.

Jun 30, 2026Read more →
Do GLP-1 Drugs Sabotage Fat Grafts? What the Latest Surgery Data Actually Shows
Research

Do GLP-1 Drugs Sabotage Fat Grafts? What the Latest Surgery Data Actually Shows

New studies show semaglutide users face a 45% complication rate in cosmetic surgery. Here's why GLP-1 drugs interfere with fat graft biology and what surgeons are doing about it.

Jun 28, 2026Read more →
Thymosin Alpha-1 in Cancer Immunotherapy: New Mechanism Restores Immunity After Chemo
Research

Thymosin Alpha-1 in Cancer Immunotherapy: New Mechanism Restores Immunity After Chemo

Three 2026 studies reveal how thymosin alpha-1 restores antitumor immunity after chemotherapy, reverses T-cell exhaustion, and synergizes with checkpoint inhibitors.

Jun 27, 2026Read more →
Semaglutide Cuts Cardiovascular Events by 25% in Rheumatoid Arthritis Patients: New Study
Research

Semaglutide Cuts Cardiovascular Events by 25% in Rheumatoid Arthritis Patients: New Study

A June 2026 study found semaglutide reduced major cardiovascular events by 25% and heart failure by 31% in obese adults with type 2 diabetes and rheumatoid arthritis, with a surprising bonus: fewer patients needed stronger RA medications.

Jun 25, 2026Read more →